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Advise pregnant women of the potential risk to a fetus. Advise females of reproductive potential to use effective contraception during treatment with an OPDIVO- or YERVOY- containing regimen and for at least 5 months after the last dose of OPDIVO. Lactation It is not known whether OPDIVO or YERVOY is present in human milk. Because many drugs, including antibodies, are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from an OPDIVO-containing regimen, advise women to discontinue breastfeeding during treatment. Advise women to discontinue nursing during treatment with YERVOY and for 3 months following the final dose. Serious Adverse Reactions In Checkmate 037, serious adverse reactions occurred in 41% of patients receiving OPDIVO (n=268). Grade 3 and 4 adverse reactions occurred in 42% of patients receiving OPDIVO. The most frequent Grade 3 and 4 adverse drug reactions reported in 2% to <5% of patients receiving OPDIVO were abdominal pain, hyponatremia, increased aspartate aminotransferase, and increased lipase. In Checkmate 066, serious adverse reactions occurred in 36% of patients receiving OPDIVO (n=206). Grade 3 and 4 adverse reactions occurred in 41% of patients receiving OPDIVO.
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Our.n-line submission system guides you stepwise through the process of entering your article details and uploading your files. State the objectives of the work and provide an adequate background, avoiding a detailed literature survey or a summary of the results. Bronchoscope is a thin flexible tube to be inserted into airways through nose or mouth or through tracheotomy. List funding sources in this standard way to facilitate compliance to funder’s requirements: Funding: This work was supported by the National Institutes of Health grant numbers xxxx, yyyy; the Bill & Melinda Gates Foundation, Seattle, WA grant number zzzz; and the United States Institutes of Peace grant number aaaa. Titles are often used in information-retrieval systems. Elsevier has preprinted forms for use by authors in these cases. Kenneth Chew | Kate Carey | Genevieve Ho | Kylie-Ann Mallitt | John wider | Michelle Farrar The multidisciplinary care of Duchenne muscular dystrophy DMZ incorporates management of nutrition and the respiratory system, however the effect of body habits on respiratory function in DMZ is… Faulkner, Angela oak, Hadley A. Pulmonology is considered a branch of internal medicine, and is related to intensive care medicine . Irving, Teresa To, for the Canadian Respiratory Research Network Adolescents with asthma had a higher odds of smoking e-cigarettes or any substance. Avoid abbreviations and formulae where possible. • Author names and affiliations.